Novel Food 2016
Reg. 2017/2470
471 · 473 · 474
NOAEL · toxicological safety
GMP production
01 · Cartilage anatomy
When it hurts, the damage has already been there for years.
Cartilage gives no warning. It has no blood vessels or nerves — that’s why by the time pain appears, the loss is already structural. What you can replenish: the cofactor that supports its matrix. Organic silicon.
Cartilage starts to break down silently at 30
The slow loss of proteoglycans begins. There are still no symptoms.
Occasional morning stiffness. The matrix loses elasticity. Prevention window.
The surface cartilage develops fissures. Pain appears when climbing stairs or after exercise.
Osteoarthritis established. Silicon replenishment becomes more necessary than ever.
The window closes at 50 — cartilage still responds — when cartilage still responds to replenishment.
Type II collagen synthesis
Silicon is an essential cofactor for the enzymes that assemble type II collagen fibers in the chondrocyte — the protein that gives cartilage its tensile strength.
Strengthening the extracellular matrix
Silicon strengthens the synthesis and stability of proteoglycans, the molecules that retain water and allow cartilage to return to its shape after impact.
Load and impact capacity
A hydrated matrix absorbs impact and returns to shape. Silicon maintains cushioning capacity; when it dehydrates, cartilage becomes stiff and vulnerable.
Subchondral bone and calcium fixation
Cartilage rests on the subchondral bone. Silicon promotes calcium fixation in the bone matrix — the base on which the whole joint rests.
G7 Activ+ · the osteoarticular formula of Silicium.
Organic silicon + magnesium + vitamin C. Three synergistic actives in one capsule designed for bones and cartilage.
Other organic silicon products for joints.
Different formulas of the same active Silicium G7®, depending on routine, intensity, and usage method.
More than 23 years of trust.
Real reviews verified by Trusted Shops · the European trust framework for online commerce.
Frequently asked questions about silicon and joints.
01When will I notice a difference taking G7 Activ+ for my joints?+
The first effects are noticed between the 4th and 8th week of regular use. In the BIOFORTIS study (Mérieux NutriSciences 2011) with 30 adults, significant improvement in mobility and pain reduction were observed after 6 weeks. Full structural regeneration requires 3-6 month cycles.
02Is G7 Activ+ for osteoarthritis or only for maintenance?+
It works in both contexts. In early osteoarthritis, silicon provides the precursors cartilage needs to repair the matrix. For maintenance (over 40 without pathology), it helps compensate for progressive physiological loss. If you have confirmed osteoarthritis, consult your doctor to coordinate it with your treatment.
03Can I combine G7 Activ+ with chondroitin or glucosamine?+
Yes, they are synergistic. Chondroitin and glucosamine provide precursors to proteoglycans (structural molecules). Silicon provides the cofactor to synthesize type II collagen and strengthens the matrix that retains those compounds. No documented interactions in 23 years.
04Is the liquid format (G7 Original) or the capsules (G7 Activ+) better for joints?+
For joints, the G7 Activ+ capsules provide the specific combination of silicon + magnesium + vitamin C in a standardized dose, more convenient for daily use and travel. The G7 Original liquid is more versatile (you can split doses), but requires more discipline to take. Both contain the same Le Ribault organic silicon.
05Is it suitable for athletes with joint overload?+
Yes, especially in high-impact disciplines (running, basketball, padel) and progressive strength training. Silicon maintains cartilage elasticity and helps prevent micro-injuries from overuse. For recovery after intense exertion or post-injury, consider G7 Sport Recovery with added zinc and L-glycine.
06What dose of G7 Activ+ should I take?+
The standard dose is 2 capsules a day, one with breakfast and one with lunch. For preventive maintenance, 1 capsule a day is enough. During periods of greater joint demand (intense sport, recovery) it can be increased to 3 capsules. Always read the instructions on the package and, if in doubt, consult your healthcare professional.
Six pages to understand Silicium in depth.
The team that supports this page.
The content is signed by the person who writes it and the person who reviews it.
Juan Carlos Hierro
Director · Silicium Laboratories Europe
Industrial lead for transferring Dr. Le Ribault's original formula since 2010. More than 23 years working with the Silicium G7® active ingredient.
Dr. Maria del Mar Sabaté Martínez
PhD in Biochemistry · Universitat Rovira i Virgili
Academic review of the active ingredient’s kinetics, usage guidelines, and clinical references. Verification of the claims against the published scientific literature.
Organic silicon that 23 years back up.
No relevant adverse effects reported, EFSA approval as a Novel Food, and 60+ studies cataloged on the active ingredient. The original Dr. Le Ribault formula, in liquid and capsule format.
The ten references.
View the 10 scientific references
- Carlisle EM (1981). Silicon: a requirement in bone formation independent of vitamin D1. Calcified Tissue Int 33:27-34. DOI
- Reffitt DM et al. (1999). OSA/MMST and collagen synthesis. Pioneering research on orthosilicic acid and MMST. DOI
- Jugdaohsingh R, Tucker KL, Qiao N, Cupples LA, Kiel DP, Powell JJ (2004). Dietary silicon intake is positively associated with bone mineral density in men and pre-menopausal women of the Framingham Offspring cohort. J Bone Mineral Res 19:297-307 · n=2.847 · up to +10 % BMD between the highest and lowest quintiles of dietary Si. DOI
- BIOFORTIS · Mérieux NutriSciences (2011). Efficacy of Silicium G7® · 30 subjects · 6 weeks · 87 % reported improved mobility · 77 % reported less pain.
- Del Bas JM et al. (2014). In vitro evaluation of Silicium G5 on bone health parameters in MG-63 cells · +12 % collagen · +40 % mineralization. Internal CTNS-Eurecat report (unpublished).
- EFSA (2016). Scientific Opinion · safety of organic silicon as a Novel Food (EU Regulation 2017/2470) · NOAEL · toxicological safety/d. DOI
- Polonini H. et al. (2018). Topical MMST permeates ≈60 % into epidermis and viable dermis (ex vivo Franz cells) · Int J Cosmet Sci. Cosmetics.
- Ferreira AO et al. (2018). 25 % wrinkle reduction (Visia) and subjective improvement in hair hydration and skin radiance · n=51 · 5 months.
- Jones K, Linhart C, Hawkins C, Exley C. (2017). Urinary excretion of aluminium and silicon in secondary progressive multiple sclerosis. EBioMedicine. DOI
- Crescenti M et al. (2025). Double-blind placebo-controlled parallel RCT · n=45 · 4 groups · 7 days · Universidad Católica de Murcia (UCAM) · Significant increase in urinary Al excretion in women with M-OSA (ORGONO_Malto, median +157 % [IQR 51,4–193] · p=0,006) · manuscript under peer-review.
Medical notice. Informational content. Does not replace consultation with a healthcare professional. During pregnancy, breastfeeding, chronic illness, or active medical treatment, consult before starting supplementation. Scientific review: Dr. Maria del Mar Sabaté Martínez (Universitat Rovira i Virgili, PhD in Biochemistry).